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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PKN1
All Species:
23.64
Human Site:
S418
Identified Species:
40
UniProt:
Q16512
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16512
NP_002732.3
942
103932
S418
G
P
N
A
W
D
Q
S
F
T
L
E
L
E
R
Chimpanzee
Pan troglodytes
XP_512443
1169
127241
S645
G
P
N
A
W
D
Q
S
F
T
L
E
L
E
R
Rhesus Macaque
Macaca mulatta
XP_001110500
1011
111864
H486
R
E
L
E
I
G
V
H
W
R
D
W
R
Q
L
Dog
Lupus familis
XP_542019
1076
118222
S551
G
P
S
A
W
D
Q
S
F
T
L
E
L
E
R
Cat
Felis silvestris
Mouse
Mus musculus
P70268
946
104392
S421
G
P
N
A
W
D
Q
S
F
T
L
E
L
E
R
Rat
Rattus norvegicus
Q63433
946
104449
S421
G
P
N
A
W
D
Q
S
F
T
L
E
L
E
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506565
993
109767
Q473
R
E
L
E
I
G
V
Q
S
K
X
X
X
X
X
Chicken
Gallus gallus
XP_422357
1013
114806
K446
S
N
Q
S
W
D
Q
K
F
T
L
E
L
D
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_689331
948
107057
T431
G
E
Q
G
W
D
Q
T
F
I
I
E
L
E
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13678
634
71138
A193
K
R
C
Q
K
N
V
A
N
T
C
G
I
N
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34885
707
80133
G266
P
T
F
C
D
H
C
G
S
M
L
Y
G
L
I
Sea Urchin
Strong. purpuratus
XP_787090
799
90414
H325
Q
R
K
I
F
P
K
H
K
G
K
N
F
L
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P24583
1151
131500
S384
L
T
L
G
F
H
K
S
S
Q
I
E
R
K
Q
Red Bread Mold
Neurospora crassa
P87253
1142
127954
A472
F
Y
N
I
M
R
C
A
L
C
G
D
F
L
K
Conservation
Percent
Protein Identity:
100
79.3
38.7
83
N.A.
91.6
91.9
N.A.
42.2
57.6
N.A.
66.7
N.A.
29
N.A.
27.8
48.5
Protein Similarity:
100
79.9
52.6
84.3
N.A.
94.7
94.6
N.A.
56.1
72.1
N.A.
79.5
N.A.
42.8
N.A.
43.4
61.7
P-Site Identity:
100
100
0
93.3
N.A.
100
100
N.A.
0
60
N.A.
60
N.A.
6.6
N.A.
6.6
6.6
P-Site Similarity:
100
100
13.3
100
N.A.
100
100
N.A.
0
73.3
N.A.
73.3
N.A.
26.6
N.A.
6.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.8
28.3
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.4
45.1
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
46.6
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
36
0
0
0
15
0
0
0
0
0
0
0
% A
% Cys:
0
0
8
8
0
0
15
0
0
8
8
0
0
0
0
% C
% Asp:
0
0
0
0
8
50
0
0
0
0
8
8
0
8
0
% D
% Glu:
0
22
0
15
0
0
0
0
0
0
0
58
0
43
0
% E
% Phe:
8
0
8
0
15
0
0
0
50
0
0
0
15
0
0
% F
% Gly:
43
0
0
15
0
15
0
8
0
8
8
8
8
0
0
% G
% His:
0
0
0
0
0
15
0
15
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
15
15
0
0
0
0
8
15
0
8
0
8
% I
% Lys:
8
0
8
0
8
0
15
8
8
8
8
0
0
8
8
% K
% Leu:
8
0
22
0
0
0
0
0
8
0
50
0
50
22
8
% L
% Met:
0
0
0
0
8
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
0
8
36
0
0
8
0
0
8
0
0
8
0
8
0
% N
% Pro:
8
36
0
0
0
8
0
0
0
0
0
0
0
0
0
% P
% Gln:
8
0
15
8
0
0
50
8
0
8
0
0
0
8
8
% Q
% Arg:
15
15
0
0
0
8
0
0
0
8
0
0
15
0
58
% R
% Ser:
8
0
8
8
0
0
0
43
22
0
0
0
0
0
0
% S
% Thr:
0
15
0
0
0
0
0
8
0
50
0
0
0
0
8
% T
% Val:
0
0
0
0
0
0
22
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
50
0
0
0
8
0
0
8
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _